Rejuvenate Your Brain with NeuroRegenex

The brain is the control center of the body and mind, and maintaining a healthy brain is vital for overall well-being. Optimizing brain health supports cognition; the ability to cope with the normal stressors of life; and allows for positive social impacts. However, modern living can compromise the management of normal brain health. Factors such as air pollution, environmental toxins, high stress levels, lack of physical activity, poor nutrition, aging, and social isolation all negatively impact on brain health via inflammatory processes and oxidative stress.^1,2 Additionally, the brain has a high metabolic rate, utilizing more than 20% of the body’s oxygen and energy. This metabolic activity naturally produces reactive oxygen species within the brain.³ Thankfully, we can support our brain health throughout our lifetimes by minimizing these risk factors, and by enhancing protective factors.^1,2 Antioxidants can aid in the maintenance of brain health by acting as free radical scavengers, mopping up reactive oxygen species and supporting the maintenance of neuronal health.³ A systematic review involving 31 human clinical trials found that consumption of plant antioxidants can help maintain healthy cognitive function in young, adult, and elderly people.⁴ Getting an adequate amount of plant-based antioxidants through diet alone can be difficult; however herbal supplements can help to boost your daily antioxidant intake.

Rejuvenating Herbal Brain Support

MediHerb® NeuroRegenex is an herbal brain tonic, that offers a specialized extract of Turmeric with FenuMAT™ technology for enhanced bioavailability of curcumin. It also contains Boswellia with FenuMAT™, Bupleurum root, and Gotu Kola extract which is standardized for triterpenes.

The herbs in NeuroRegenex work:

• To tonify the brain and support healthy mental clarity, cognition and memory function, as used traditionally in Ayurveda*
• Rejuvenate and support the body’s natural ability to adapt to temporary stress, as used traditionally in Ayurveda*
• To support a healthy inflammatory response*
• To support systemic antioxidant activity*

MediHerb® NeuroRegenex is a unique formulation that provides a specialized, bioavailable form of curcumin from Turmeric. The extent to which a substance is absorbed and therefore available to the body is called bioavailability. Unformulated Turmeric is known to have low bioavailability.⁵ However, this advanced extract of Turmeric harnesses FenuMAT™ technology to enhance its bioavailability. FenuMAT™ utilizes Fenugreek galactomannans: a natural prebiotic fiber that forms a self-emulsifying protective hydrogel that protects Turmeric’s active phytochemicals

(known as curcuminoids and curcumin) from degradation in the upper gastrointestinal tract. FenuMAT™ also increases attachment to the gastric mucosa, allowing slow release into the epithelium, promoting direct absorption into circulation and the lymphatic system.⁶ Curcumin with FenuMAT™ technology has demonstrated 45-times greater systemic bioavailability of free curcumin compared to unformulated curcumin.⁷

Supports the Body’s Antioxidant and Natural Inflammatory Response Processes

Turmeric has been used as a food and in herbal preparations for thousands of years. It has a long list of traditional health benefits across several cultural healthcare systems, including Ayurveda, traditional Chinese practice, and traditional Islamic herbal practice. Modern science supports this long tradition, with Turmeric and its key active phytochemical curcumin being well studied in the scientific literature.⁸ It is well known to support a healthy inflammatory response,⁹ by supporting the body’s management of immunological mediators.^10,11,12 It is also a well-regarded antioxidant*.¹⁰

Contains Boswellia

Boswellia oleoresin is one of the oldest and most highly valued herbs in the Ayurvedic and Unani traditions. The resin contains various terpenes, the most important of which are the pentacyclic triterpenes collectively known as boswellic acids.¹³

Tonifies the Brain

In Ayurveda, Gotu Kola is a key herb used for the revitalization of the nerves and brain. It is considered a Medhya-Rasayana herb, or rejuvenating brain tonic. It is commonly used to support healthy cognition and memory function*.¹⁴

Supports the Body’s Natural Ability to Respond to Stress

Gotu Kola is a key Rasayana herb in Ayurveda. Rasayanas are said to act as adaptogens - substances which support the body’s resistance to everyday mild stressors and support normal physiological functioning. Rasayanas are also said to enrich the tissues, rejuvenate body and mind, promote healthy aging, vitality, vigor, and intellect*.¹⁴

Contains Bupleurum

Bupleurum is an important remedy in traditional Chinese and Kampo herbal practice. In this tradition, 3-9 g day of dried root preparations are used to spread Liver Qi, which helps to soothe occasional emotional distress and irritability associated with Liver Qi stagnation.¹⁵ Bupleurum naturally contains triterpene saponins, including saikosaponins*.¹⁶

Better Together

MediHerb® NeuroRegenex can be combined with other MediHerb herbal products to provide greater support for health and wellbeing.

NeuroRegenex combines well with:

• Nevaton Forte, to support healthy mood balance*
• Bacopa Complex, for healthy cognition*
• Vitanox, for antioxidant support*
• HerbaVital, for healthy aging*
• Boswellia Complex, for a healthy inflammatory response*
• Ashwagandha Complex, to support a normal, healthy stress response*

Conclusion

By supporting our brain’s resilience capacity, we can continue to enjoy healthy cognitive function, emotional well-being, and overall quality of life. Herbs that offer antioxidant activity, that support normal inflammatory responses, and that tonify and rejuvenate the brain may help to maintain our brain health throughout life.²

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

References

1. World Health Organization. Optimizing brain health across the life course: WHO position paper. Geneva: World Health Organization; 2022 [cited September 9 2024]. Available from: https://iris.who.int/bitstream/handle/10665/361251/9789240054561-eng.pdf?sequence=1
2. McKinsey Health Institute. What is brain health? New York: McKinzey and Company; 2023 [cited September 9 2024]. Available at: https://www.mckinsey.com/featured-insights/mckinsey-explainers/what-is-brain-health
3. Gomez-Pinilla F, Nguyen TTJ. Natural mood foods. Nutr. Neurosci. 2012 May;15(3):127-33. DOI:10.1179/1476830511Y.0000000035
4. Baroni L, Sarni AR, Zuliani C. Plant foods rich in antioxidants and human cognition: a systematic review. Antioxidants. 2021 Apr 30;10(5):714. DOI:10.3390/antiox10050714
5. Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: problems and promises. Mol Pharmaceutics. 2007 Dec 1;4(6):807-18. DOI:10.1021/mp700113r
6. Arkay Natural Ingredients. Technology [Internet]. Kerala: Arkay Natural Ingredients; 2021 [cited 2022 Feb 09]. Available from: https://www. curqfen.net/technology/#
7. Kumar D, Jacob D, Subash PS, Maliakkal A, Johannah NM, Kuttan R, et al. Enhanced bioavailability and relative distribution of free (unconjugated) curcuminoids following the oral administration of a food-grade formulation with fenugreek dietary fibre: a randomised double-blind crossover study. J Funct Foods. 2016 Apr 1;22:578-87.
8. Akaberi M, Sahebkar A, Emami SA. Turmeric and curcumin: from traditional to modern medicine. Studies on Biomarkers and New Targets in Aging Research in Iran: Focus on Turmeric and Curcumin. Adv Exp Med Biol. 2021;1291:15-39.
9. Health Canada, ‘Curcmin’, Aug 28, 2018. Accessed 20/07/2020 from http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=curcumin.curcumine&lang=eng
10. Sahebkar A, Cicero AFG, Simental-Mendía LE, Aggarwal BB, Gupta SC. Curcumin: a systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2016;107:234-242. doi:10.1016/j.phrs.2016.03.026 Meta-analysis / PS
11. Derosa G, Maffioli P, Simental-Mendía LE, Bo S, Sahebkar A. Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2016;111:394-404.doi:10.1016/j.phrs.2016.07.004
12. Yu Y, Shen Q, Lai Y, Park SY, Ou X, Lin D, Jin M, et al. Front Pharmacol. 2018 Apr 20;9:386. https://doi.org/10.3389/fphar.2018.00386
13. Siddiqui MZ. Boswellia serrata: an overview. Indian J Pharm Sci. 2011 May;73(3):255-61. doi: 10.4103/0250-474X.93507
14. Chaudhry B. Key Rasayana Plants of Ayurveda. EWIJST. 2021 Apr 10;16:53-73.
15. Chen JK, Chen TT. Chinese medical herbology and pharmacology. Art of Medicine Press, USA, 2012.
16. World Health Organization. WHO monographs on selected medicinal plants. World Health Organization, Volume 1, Geneva, 1999, pp. 67-76.